Department of Biological Sciences
Plant flavonoid metabolism
Flavonoids are specialized plant metabolites that have potent physiological activities, both in plants and in other organisms, including humans. The Winkel laboratory has performed ground-breaking work in characterizing the intracellular organization of the flavonoid biosynthesis pathway, using Arabidopsis thaliana as model organism. Current work uses cryo-EM and proteomics to study dynamic multi-enzyme complexes involved in flavonoid biosynthesis and explores the links between flavonoids and the circadian clock in plants.